Sintra business park, zona industrial da abrunheira, edificio 10, 2710089 sintra portugal. Internationala a substantei active este ciclofosfamida. Each tablet contains cyclophosphamide monohydrate equivalent to 50 mg anhydrous cyclophosphamide. Endoxan poate fi utilizat singur sau in asociere cu alte medicamente. To report suspected adverse reactions, contact baxter healthcare at 18668882472 or fda at 1800fda1088 or. A ciclofosfamida pode aumentar a atividade dos anticoagulantes orais.
Provavel aumento na toxicidade devido a ciclofosfamida. Handle and dispose of cyclophosphamide in a manner consistent with other cytotoxic drugs. Cyclophosphamide is an alkylating agent, and prevents. As an immune suppressor it is used in nephrotic syndrome. Cyclophosphamide therapy is associated with minor transient serum enzyme elevations and has been linked to rare cases of acute liver injury. Cyclophosphamide 50 mg tablets by caroline mcdermott at this product is available as the above name but will be referred to as cyclophosphamide throughout the following leaflet. Docetaxel taxotere e ciclofosfamida cytoxan, lidando com efeitos colaterais. Cyclophosphamide for injection, usp is a sterile white powder containing cyclophosphamide monohydrate. The effects of cyclophosphamide on the prolactin cells of. Cyclophosphamide is a white crystalline powder with the molecular formula c 7 h 15 cl 2 n 2 o 2 p h 2 o and a molecular weight of 279.
Cyclophosphamide for injection, usp cyclophosphamide tablets, usp description cyclophosphamide for injection, usp is a sterile white powder containing. Read all of this leaflet carefully before you start taking this medicine because it contains important information for you. Norwegian researchers have commenced phase ii trials of the anticancer drug cyclophosphamide on mecfs patients led by senior consultant dr oystein fluge and prof olav mella, the team is focusing on nonresponders and those patients who have relapsed after treatment with rituximab, a bcell depleting drug. Combined protective effect of zinc oxide nanoparticles and melatonin on cyclophosphamideinduced toxicity in testicular histology and sperm parameters in adult wistar rats. As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma. What are the generic drug sources for cyclophosphamide and what is the scope of patent protection cyclophosphamide is the generic ingredient in five branded drugs marketed by ani pharms inc, cipla, hikma, sti pharma llc, amneal, baxter hlthcare, jiangsu hengrui med, bedford, teva parenteral, and roxane, and is included in sixteen ndas. Generic cyclophosphamide inn entry, pharmaceutical patent and. Immunosuppressive effect of cyclophosphamide on white blood. Additional information is available in the individual branded drug profile pages. If you become pregnant while having endoxan, tell your doctor. Immunosuppressive effect of cyclophosphamide on white. It is best to read this information with our general information about chemotherapy and the type of cancer you have your doctor will talk to you about this treatment and its possible side effects before you agree consent to. It is best to read this information with our general information about chemotherapy and the type of cancer you have. Cyclophosphamide is a cytotoxic drug for the treatment of malignant disease in adults and children.
Vials containing 200 mg, 500 mg, and 1 g cyclophosphamide as powder per vial. Cyclophosphamide fda prescribing information, side. Endoxan ciclofosfamida bula do medicamento folhetos. Ciclofosfamide universita degli studi dellinsubria. Eine trockenstechampulle enthalt 2,8 mg cyclophosphamidmonohydrat entsprechend 200 mg. Craig, united states says, seemed easy to purchase, reasonable prices. There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk e. Adrian simpson, united states says, if you are looking for a fair deal on medical supplies, idm is something i would seriously recommend. C 7 h 1 5 cl 2 n 2 o 2 p marcela rosario fernandez 05jun2007 7. Cyclophosphamide is a synthetic antineoplastic drug chemically related to the nitrogen mustards. If you have any further questions, ask your doctor or pharmacist. Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
To report suspected adverse reactions, contact baxter. Cyclophosphamide fda prescribing information, side effects. Cyclophosphamide is an alkylating agent of the nitrogen mustard type. Poblador, carmen rojas, antonio raya, joaquin quiralte, jose a. Both men and women taking endoxan and their partners must use a reliable method of contraception during and for 3 months after receiving endoxan.
Casares and jose luis lancho alonso department of morphological sciences, human anatomyneuroanatomy section, faculty of medicine, university of cordoba, spain summary. Pdf combined protective effect of zinc oxide nanoparticles. The effects of cyclophosphamide on the prolactin cells of the normal rat maria s. Request pdf on apr 28, 2011, xiaohui huyan and others published immunosuppressive effect of cyclophosphamide on white blood cells and lymphocyte subpopulations from peripheral blood of. Tablets containing 50 mg cyclophosphamide per tablet pharmacological classification. Cyclophosphamide is used to treat breast cancer, lung cancer, leukaemia, lymphoma, and myeloma. Cyclophosphamide cp, also known as cytophosphane among other names, is a medication used as chemotherapy and to suppress the immune system. Endoxan ciclofosfamida bula do medicamento folhetos, bulas. In addition, when given in high doses as a part of a myeloablative.
Bitte sprechen sie mit ihrem arzt oder apotheker, bevor sie cyclophosphamid anwenden. Apr 29, 2020 cyclophosphamide is the generic ingredient in five branded drugs marketed by ani pharms inc, cipla, hikma, sti pharma llc, amneal, baxter hlthcare, jiangsu hengrui med, bedford, teva parenteral, and roxane, and is included in sixteen ndas. Endoxan cyclophosphamide is a cyclic propylene phosphamide ester of nitrogen mustard. Ciclofosfamida, neosar, citoxan, genuxal, citofosfana. Decrease in the activities of lysosomal enzymes may contribute to the urotoxicity of cyclophosphamide in the rat premila abraham 1, indirani kanakasabapathy 2 and emila sugumar 1. Read all of this leaflet carefully before you start taking this medicine. The chemical name for cyclophosphamide is 2 h1,3,2oxazaphosphorin2amine, n,nbis2chloroethyltetrahydro, 2oxide, monohydrate.
Neosar, citoxan, genuxal, citofosfana, endoxan estado. Laboratorio baxter medicamento farmaco endoxan composicion. Order generic for cytoxan cyclophosphamide ciclofosfamida. Endoxan may cause birth defects if either the male or female is being treated with it at the time of conception. Brian pavey, united states says, idm makes online shopping a pleasure. White round biconvex sugar coated tablets with a white core.
Genuxal ciclofosfamida monoidratada baxter hospitalar ltda. Decrease in the activities of lysosomal enzymes may. The effects of cyclophosphamide on the prolactin cells of the. Associada ao alopurinol, ocorre prolongamento da meiavida da ciclofosfamida. Cyclophosphamide is an alkylating drug indicated for treatment of. New zealand data sheet endoxan data sheet 1 august 2018 page 5 of 22 baxter healthcare ltd in principle, the fall in the peripheral blood cell and thrombocyte count and the time taken to recover may increase with increasing doses of cyclophosphamide. Generic cyclophosphamide inn entry, pharmaceutical patent. Caution should be exercised when handling and preparing cyclophosphamide for injection, usp lyophilized powder, or bottles containing cyclophosphamide tablets. Request pdf on apr 28, 2011, xiaohui huyan and others published immunosuppressive effect of cyclophosphamide on white blood cells and lymphocyte subpopulations from peripheral blood of balbc. Ciclofosfamida indicaciones, dosificacion, presentacion. As a single agent, it has successfully produced an. Composicion, indicaciones, presentacion y contraindicaciones.
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